YES!
You guys, I found something *amazing* on the Internet.
There's this guy who made a WineSkin wrapper/tool thing that lets you play games inside MacOS like you're running a Windows machine. Here's his site's page on Rayman 2:
http://paulthetall.com/rayman-2-mac/
He also has something called the Porting Kit which has this whole page full of games on their servers that have already succesfully been ported. It's pretty good, at first glance. I was able to install Rayman 2 and play it. No lag, no virtual machine, all working fine.
The only comments I have so far is that it looks like 1990s graphics, which of course is bad, but does give me an immense sense of nostalgia because it reminds me of how Rayman 2 looked when I first played it. I'll investigate if I can up the graphics to make it more on-par with what we're used to from R2 on our current day machines.
Also, when you launch the game, the screen flickers a considerable amount of times and may fill up with a white square inside of black nothingness, which is scary at first - but then it actually runs fluently and without trouble. Great success!
Will update with future findings in this or a next post.
--UPDATE--
Managed to get it looking like Rayman 2 generally does on current-gen PCs!
What to do is this:
After installing the Rayman 2 app on the Porting Kit (Library > Server tab > download the wrapper > go to GOG.com > download the Windows installer and leave it in your Downloads folder > let the wrapper in the Porting Toolkit run through its installation procedure and follow all instructions, including the one telling you to press "cancel" when it prompts you for a Gecko installation - have patience; the process takes a while), go to your Local tab in Library and right click the Rayman 2 app. Select Properties.

Click Advanced and Browse on the first tab in Advanced.

Browse to the nglide_config.exe inside the created Rayman 2 app.

Test Run the nglide_config.exe.

Select the following options:
Screen Resoltion - By Desktop
Aspect Ratio - 4:3

Next, set the WineSkin options to emulate a Windows XP computer ( Tools tab > Config Utility (winecfg) ). Apply and close.

And finally, on the Configuration tab, Browse back to your Rayman2.exe executable inside the Rayman 2 app's directory (clicking Browse automatically takes you inside the app dir).

Click Test Run to see if it works. If it does, close this Advanced Wineskin window and from hereon forwards, whenever you click Play in the Porting Kit, you'll have Rayman 2 running on your Mac desktop like it were a Windows XP computer, with correct aspect ratio and using your screen's resolution.
Note: there will still be the status bar at the top of the screen. If you find that annoying, feel free to experiment and tell me how to remove it if you find a way. I don't find it annoying so I didn't bother finding out how - sorry.
This will get Rayman 2 running on your Mac and looking like a current-gen computer running it. It will still just be 4:3, not widescreen, and not have fancy graphics. Now, I am content with this and thus did not pursue further tweakings following this process. You, however, are more than welcome trying deton24's various instructions on how to get this game working in widescreen, using a similar approach as I've done here. Good luck. Let me know if it works.
The benefit of this Rayman 2 version over normal Windows machines running the game: you can minimise the window and the game will turn into Rayman II - paused like on Windows, but instead, it won't crash when you try to reopen the game from minimisation.
