I recently was able to play the N64 version of Tonic Trouble using the sixtyforce emulator and a file from wowroms (other emulators can be downloaded from this site). There were some problems:
- Graphical glitches/errors from time to time (example in the attachments).
- The game slows down if you use fullscreen.
- The music at times was played at a different speed.
- No saving and a watermark in the screen unless you register.
However, despite that I was able to 100% the game. It was nice to revisit this world again, but I still prefer the PC version. When I was a kid I perceived these levels as extensive, specially the Pyramid one, but now some of them look kind of short to me. Also, when I went for the second time to the Glacier Cocktail, a tomato jumped onto the well and blocked the entrance (screencap in the attachments), I wonder is that is something that normally happens since I don't remember it.
The sixtyforce emulator has some options you can play with to fix some of the problems, but they don't always work.